Pharmaceutical study and Analysis of Gudoochi (Tinospora cordifolia Willd) Arka

Keywords: Arka Kalpana, Arka Prakasha, Ayurveda Sara Sangraha, Gudoochi Arka, GC-MS


Introduction: Arka Kalpana is one among the extraction methods in Ayurveda, where volatile bioactive compounds of a drug are extracted using hydro-distillation process. The authentic references of Arka Kalpana are available in the classical text book Arka Prakasha. The book Ayurveda sara sangraha is another reliable source which provides guidelines regarding the general method of preparation of Arka. Various Arka formulations, its dose and indications have been described in Ayurveda Sara Sangraha. Arka as a dosage form is potent, palatable, received by patients, with a comparative long shelf life without adding any preservatives. 

Method: The present work deals with the preparation and GC-MS analysis of Gudoochi Arka.
Result: GC-MS studies had revealed that the bioactive compound detected in Gudoochi Arka in the decreasing order of their abundance is 1-Docosene, 1-Nonadecene, E-15-Heptadecenal, Phenol, 2, 4-bis (1, 1-dimethylethyl)-, 1-Eicosanol, Trichloroacetic acid, pentadecyl ester, 10-Heneicosene (c,t), Heptadecane, 9-hexyl. 

Conclusion:Analysing the properties of these bioactive compounds, it was understood that they exhibit clinical activities like anti-inflammatory, antioxidant, antimicrobial, anticancer, antifungal, Hypocholesterolemic activities which ensures that this formulation can be used for a wide range of ailments.

Author Biography


PG Scholar

Government Ayurveda Medical College





Agnivesha, Charaka Samhitha, Chakrapani Datta, Ayurveda Deepika Vyakhyana, Sutrasthana, Chaukhamba Surbharati Prakashan, Rp 2009 ,Chapter 4 , p. 31 , Sloka 7.

Lankapathi Ravana, Dr.Indradev Tripati. Arka Prakasha. (4thed)Varanasi: Chowkambha Krishnadas Academy. 2015. Chapter 1 pg. 1-2. Sloka 3-8.

Sri Sadanantha, Sarma, Sri Haridatta, Sastri, Pandit, Sastri. Rasatarangini. (11 ed.). New Delhi: Motilal Banarasi das; 2014.chapter 4 Pg 57-58, sloka 42-46

Sri Sadanantha, Sarma, Sri Haridatta, Sastri, Pandit, Sastri. Rasatarangiini. (11 ed.). New Delhi: Motilal Banarasi das; 2014.chapter 4 Pg 57-58, sloka 42-46.

Ayurveda Sara Sangraha, Alahabhad, Sri Baidhyanath Ayurveda Bhavan Ltd, 2018 Pg. 641-649.

Selvaraj, C. ImmanuelRavi, Lokesh,Ruthiran, Papitha , Phytochemical Screening, FT-IR and Gas Chromatography Mass Spectrometry Analysis of Tinospora cordifolia (Thunb.) Miers International Journal of Pharmacognosy and Phytochemical Research, VL - 8,PY - 2016/12/04 SP - 2020 EP - 2024.

Wagay N.A., Yatoo Ghulam Mohiuddin, Khan N.A., Phytochemical evaluation and identification of bioactive compounds in camel thorn alhagi pseudalhagi (M. BIEB.) DESV. EX B. KELLER & SHAP. STEM, International Journal of Advance Research in Science and Engineering,VL-07, SI- No: 04, March 2018

Devakumar J, Keerthana V, Sudha S S, Identification of Bioactive Compounds by Gas Chromatography-Mass Spectrometry Analysis of Syzygium Jambos (L.) Collected From Western Ghats Region Coimbatore, Tamil Nadu, Vol 10, Issue 1, 2017, Online - 2455-3891 Print - 0974-2441.

P Vani et al. Phytochemical investigation, antibacterial activity and antioxidant activity of the endangered Commiphora wightii (Arn.) Bhandari , Journal of Pharmacognosy and Phytochemistry ; 2016 JPP 2016; 5(5): 22.

Krishnamoorthy K, Subramaniam P. Phytochemical Profiling of Leaf, Stem, and Tuber Parts of Solena amplexicaulis (Lam.) Gandhi Using GC-MS. Int Sch Res Notices. 2014; 2014:567409. Published 2014 Jul 14. doi:10.1155/2014/567409.

Elsayed, Tarek, Galil, Diana,Sedik, Mohammed,Hassan, Hazem.Sadik, Mahmoud ,PY-2020/09/11,Antimicrobial and Anticancer Activities of Actinomycetes Isolated from Egyptian Soils, International Journal of Current Microbiology and Applied Sciences, VL - 9,DO -10.20546/ijcmas.2020.909.209 .

Chatterjee, Soumendranath,Karmakar, Amarnath Azmi, Syed Barik, Anandamay Antibacterial Activity of Long-Chain Primary Alcohols from Solena amplexicaulis Leaves, DO - 10.1007/s12595-017-0208-0, PY - 2017/02/13.

Mayuri Chelkar, Mahesh Harke and Arul Pandiyan Identification of chemical compounds from the ethanolic extract of Bauhinia racemosa Lam. Bark by GC-MS analysis The Pharma Innovation Journal 2020; 9(11): 11-13.

How to Cite
EBIN T U. Pharmaceutical study and Analysis of Gudoochi (Tinospora cordifolia Willd) Arka. IJATM [Internet]. 2021Jun.30 [cited 2022Jan.23];3(4):11-5. Available from: