Ayurvedic Approach to Etiopathogenesis, Management and Prevention of Hyperlipidaemia.

Hyperlipidemia -An Ayurvedic View


  • Dr. Shankar Gautam P.G. Department of Kayachikitsa National Institute of Ayurveda, Jaipur-302002, Rajasthan, India
  • Dr. Ram Kishor Joshi Professor and Head of P.G. Department of Kayachikitsa National Institute of Ayurveda, Jaipur-302002, Rajasthan, India
  • Dr. Abhishek Upadhyay P.G. Department of Kayachikitsa National Institute of Ayurveda, Jaipur-302002, Rajasthan, India
  • Dr. Hari Khanal P.G. Department of Kayachikitsa National Institute of Ayurveda, Jaipur-302002, Rajasthan, India
  • Dr. Binod Kumar Singh P.G. Department of Kayachikitsa National Institute of Ayurveda, Jaipur-302002, Rajasthan, India


Dyslipidaemia, Hyperlipidaemia, Medoroga, Medovaha Srotodusti Vikara, Sthaulya


Introduction: Hyperlipidaemia refers to the elevation of plasma cholesterol, triglycerides or a low level of high-density lipoprotein that contributes to the development of atherosclerosis, a precursor for ischemic heart disease. It has been identified as a potential risk factor for many diseases including cardiovascular diseases, metabolic syndrome and hypertension. The objectives of this study is to explore Ayurvedic literature for understanding and establishing the pathophysiology, prevention and treatment of hyperlipidaemia.

Methods: The Ayurvedic etiopathogenesis, prevention and management has been compiled using relevant terms in various classical Ayurvedic texts and Nighantus. Evidence-based articles published online within databases (Pubmed and Google scholars)  have been reviewed.

Results: In Ayurvedic view, hyperlipidaemia can be considered similar to aggravated Dusta Meda Dhatu in the body which is caused due to hypofunction of Medo-Dhatwagni leading to Medovaha Srotodusti Vikara. It can be cured and prevented with certain lifestyle modifications like a low carbohydrate and fat diet, regular physical exercise and with Ayurveda modalities viz. Shodhana and Shamana Chikitsa. Different research studies carried out on several herbs and Ayurveda drugs confirmed hypolipidemic activities.

Conclusions: Ayurveda approaches have the solution for hyperlipidaemia, not only on management but also on its prevention. Further clinical researches are needed for its scientific validation.


Mushtaq, M., U. Sadique, N. Chand, I. Ahmed, S.S.A. Shah, I. Ahmad, Imran-Ullah and M. Shah. 2016. Biochemical effect of water based infusion of Withania somnifera in broiler production. Meat Sciences and Veterinary Public Health, 1(1): 17-20.

National Research Council (US) Committee on Diet and Health. Diet and Health: Implications for Reducing Chronic Disease Risk. Washington (DC): National Academies Press (US); 1989. 7, Fats and Other Lipids. Available from: https://www.ncbi.nlm.nih.gov/books/NBK218759/

Lilly, Leonard S. Pathophysiology of heart disease: a collaborative project of medical students and faculty. Lippincott Williams & Wilkins, 2012.

Valentin Fuster, Wayne R, Robert A O’Rourke. Hurst’s The Heart. Volume 1, 10 th Ed. New Delhi: McGraw-Hill Medical Publishing Division, 2001; p. 6.

Kumari H, Pushpan R, Nishteswar K. Medohara and Lekhaniya dravyas (anti-obesity and hypolipidemic drugs) in Ayurvedic classics: A critical review. Ayu. 2013 Jan;34(1):11-6. doi: 10.4103/0974-8520.115437. PMID: 24049399; PMCID: PMC3764867.

Yadavji Trikamji Acharya, editor. Caraka Samhita. Varanasi: Chaukhamba Surbharati Prakashana, 2017.

Kebal Krishna Thakral, commentator. Susruta Samhita. Varanasi: Chaukhambha Orientalia, Second Ed. 2016.

Brahmasankara Mishra, Rupalalji Vaisya, editor. Bhavaprakasa. Varanasi: Chaukhambha Sanskrit Sansthan, Part 1, Eighth Ed. 1997. Purvakhanda, Mishraprakaranam, Verse 177. p. 184.

Indradeva Tripathi, editor. RajaNighantu. Varanasi: Chowkhamba Krishnadas Academy.

Priya Vrat Sharma, editor. Dhanwantari Nighantu. Varanasi: Chaukhamba Orientalia, Reprint Ed. 2008. Chapter 5 Amradi varga, Verse 85. p. 163.

Gyanendra Pandeya, editor. Madanapala Nighantu. Varanasi: Chaukhamba Orientalia. First Ed.2012. Paniyavarga, Verse 36. p. 582.

Priyavrata Sharma, Guru Prasad Sharma, editor. Kaiyadeva Nighantu. Varanasi: Chaukhambha Orientalia, Reprint 2009. Dravavarga, Verse 75. p. 334.

Petruk KC. The Modern Plague of Obesity: A Holistic Guide to Challenge the Major Health Threat of the 21st Century. FriesenPress; 2020 May 6. Available from https://books.google.co.in Accessed on 28th October 2020.

Shattat, Ghassan F. "A review article on hyperlipidemia: types, treatments and new drug targets." Biomedical and Pharmacology Journal 7.1 (2015): 399-409.

Brahmanand Tripathi, editor. Astangahridaya. Delhi: Chaukhamba Sanskrit Pratishthan, Reprinted 2014. Sutrasthana Chapter 2 verse 15. p. 32.

Brahmashankar Mishra, editor. Chakradatta. Varanasi: Chowkhamba Sanskrit Series Office, 7th Ed. 2012.

Siddhi Nandan Mishra, editor. Bhaisajya Ratnavali. Varnasi: Chaukhamba Surbharati Prakashan, Ed.2017.

Brahmasankar Misra, Rupalalaji Vaisya, editor. Bhavaprakasa of Bhava Misra. First Part. Varanasi: Chaukhamba Sanskrit Sansthan, Eighth Ed. 1997. Purvakhanda, Haritakyadi varga, verse 62-64. p. 16.

Gyanendra Pandeya, editor. Madanapala Nighantu. Varanasi: Chaukhamba Orientalia. First Ed.2012. Chapter 2 Shunthyadi Varg, p. 266.

Krishna Gopala, Rasa Tantra Sara wa Siddha Prayoga Sangraha, Part 2. Rajasthana: Krisna Gopala Ayurveda Bhawana,18th Ed. 2015. Chapter 30 Medoroga p. 190

Jain Sapan B. Clinical Evaluation of Medohar Guggul and Triphala Guggul in the Management of Obesity. Indian Journal of Medical Research and Pharmaceutical Sciences 2014;1:14–20.

Brahmanand Tripathi, editor. Sarngadhara Samhita. Varanasi: Chaukhamba Surbharti Prakashan, Ed. 2017. Verse no. 2/4. p. 18.

Miller TD, Balady GJ, Fletcher GF. Exercise and its role in the prevention and rehabilitation of cardiovascular disease. Ann Behav Med. 1997 Summer;19(3):220-9. doi: 10.1007/BF02892287. PMID: 9603697.

Krishnaveni M, Mirunalini S. Therapeutic potential of Phyllanthus emblica (amla): the ayurvedic wonder. J Basic Clin Physiol Pharmacol. 2010;21(1):93-105. doi: 10.1515/jbcpp.2010.21.1.93. PMID: 20506691.

Antony B, Merina B, Sheeba V, Mukkadan J. Effect of standardized Amla extract on atherosclerosis and dyslipidemia. Indian journal of pharmaceutical sciences. 2006;68(4).

Rao TP, Sakaguchi N, Juneja LR, Wada E, Yokozawa T. Amla (Emblica officinalis Gaertn.) extracts reduce oxidative stress in streptozotocin-induced diabetic rats. J Med Food. 2005 Fall;8(3):362-8. doi: 10.1089/jmf.2005.8.362. PMID: 16176148.

Gopa B, Bhatt J, Hemavathi KG. A comparative clinical study of hypolipidemic efficacy of Amla (Emblica officinalis) with 3-hydroxy-3-methylglutaryl-coenzyme-A reductase inhibitor simvastatin. Indian J Pharmacol. 2012 Mar;44(2):238-42. doi: 10.4103/0253-7613.93857. PMID: 22529483; PMCID: PMC3326920.

Thakur CP, Thakur B, Singh S, Sinha PK, Sinha SK. The Ayurvedic medicines Haritaki, Amala and Bahira reduce cholesterol-induced atherosclerosis in rabbits. Int J Cardiol. 1988 Nov;21(2):167-75. doi: 10.1016/0167-5273(88)90219-7. PMID: 3225068.

Ekanayaka RA, Rupasinha AD, Sooriyarachchi MR, Goonaratna C. The effect of triphala, a herbal Ayurveda formulation, on serum lipids, in patients on a maintenance dose of atorvastatin for hyperlipidaemia: a randomized controlled trial. Ceylon Med J. 2017 Sep 30;62(3):128-140. doi: 10.4038/cmj.v62i3.8516. PMID: 29072054.

Babu PS, Srinivasan K. Hypolipidemic action of curcumin, the active principle of turmeric (Curcuma longa) in streptozotocin induced diabetic rats. Mol Cell Biochem. 1997 Jan;166(1-2):169-75. doi: 10.1023/a:1006819605211. PMID: 9046034.

Sharma H, Chandola HM. Prameha in Ayurveda: correlation with obesity, metabolic syndrome, and diabetes mellitus. Part 2--management of Prameha. J Altern Complement Med. 2011 Jul;17(7):589-99. doi: 10.1089/acm.2010.0397. Epub 2011 Jun 13. PMID: 21668351.

Banerjee S, Bhattacharjee P, Kar A, Mukherjee PK. LC-MS/MS analysis and network pharmacology of Trigonella foenum-graecum - A plant from Ayurveda against hyperlipidemia and hyperglycemia with combination synergy. Phytomedicine. 2019 Jul;60:152944. doi: 10.1016/j.phymed.2019.152944. Epub 2019 May 29. PMID: 31178235.

Prasad K, Mantha SV, Kalra J, Lee P. Prevention of Hypercholesterolemic Atherosclerosis by Garlic, an Antioxidant. J Cardiovasc Pharmacol Ther. 1997 Oct;2(4):309-320. doi: 10.1177/107424849700200409. PMID: 10684472.

Alizadeh-Navaei R, Roozbeh F, Saravi M, Pouramir M, Jalali F, Moghadamnia AA. Investigation of the effect of ginger on the lipid levels. A double blind controlled clinical trial. Saudi Med J. 2008 Sep;29(9):1280-4. PMID: 18813412.

Yamada T, Sugimoto K. Guggulsterone and Its Role in Chronic Diseases. Adv Exp Med Biol. 2016;929:329-361. doi: 10.1007/978-3-319-41342-6_15. PMID: 27771932.

Urizar NL, Moore DD. GUGULIPID: a natural cholesterol-lowering agent. Annu Rev Nutr. 2003;23:303-13. doi: 10.1146/annurev.nutr.23.011702.073102. Epub 2003 Feb 26. PMID: 12626688.




How to Cite

Gautam S, Joshi RK, Upadhyay A, Khanal H, Singh BK. Ayurvedic Approach to Etiopathogenesis, Management and Prevention of Hyperlipidaemia.: Hyperlipidemia -An Ayurvedic View. IJATM [Internet]. 2020 Dec. 25 [cited 2024 Feb. 21];2(3):22-30. Available from: https://ijatm.org/index.php/ijatm/article/view/45




Most read articles by the same author(s)